How does Peptest work?
Peptest analyses clinical samples, such as saliva or sputum, for the presence of pepsin. Pepsin is a stomach enzyme and because it is only produced in the stomach, if found in the oesophagus, throat, mouth or respiratory tract, it is indicative of retrograde reflux episodes. The severity of reflux can be determined based on the concentrations of pepsin found.
Peptest utilises a double monoclonal antibody capture technique incorporated into a lateral flow device. The results of the test are quantified using a small lateral-flow-reader that can be used in the lab, clinic, or GP practice. By measuring pepsin levels, clinicians are able to provide the best and most appropriate treatment for each patient.
The Peptest is capable of identifying and quantifying Pepsin across a diverse array of clinical samples, including but not limited to saliva, sputum, oesophageal aspiration, gastric juice, and bronchoalveolar fluid. This test has applications in various fields of medicine too such as gastroenterology, ear, nose, and throat (ENT) and respiratory medicine.
The field of gastroenterology utilises this diagnostic tool to aid in identifying and guiding treatment for patients who are experiencing gastroesophageal reflux disease (GORD).
In the context of Ear, Nose, and Throat (ENT) medicine, Peptest can assist in the clinical evaluation of Laryngopharyngeal reflux (LPR), also known as “Silent Reflux,” in patients experiencing symptoms such as persistent coughs, voice problems, sore throats, or a feeling of a lump in their throat. This diagnostic tool can be valuable for ENT specialists in aiding their investigations and ultimately aiding in the diagnosis of LPR.
Finally, Peptest is a diagnostic tool that can be used in respiratory medicine to investigate non-acid reflux in patients with respiratory conditions. Chronic respiratory conditions such as asthma are often linked to non-acid reflux, which is one of the most common causes. Peptest provides a measurable and unbiased assessment of pepsin levels, assisting in the identification of the underlying cause.
Diagnose a range of conditions
Peptest offers an objective measurement of pepsin in clinical samples obtained from the upper gastrointestinal and respiratory tracts, which serves as an essential marker for reflux. This measurement provides valuable diagnostic information, enabling healthcare professionals to make accurate and effective treatment decisions in sometimes difficult cases. Peptest can be used to diagnose and direct treatment for a wide range of conditions, including Gastroesophageal reflux (GORD), laryngopharyngeal reflux (LPR), chronic cough, cystic fibrosis, post-lung transplant rejection, asthma, and sinusitis. By identifying these conditions early, healthcare professionals can prevent further complications, such as the development of long-term health problems and a poor quality of life for the patient.
Untreated gastro-oesophageal reflux disease or laryngopharangeal reflux disease can lead to chronic conditions and unpleasant symptoms, including heartburn, difficulty swallowing, and voice problems. If left untreated, prolonged exposure of oesophageal and laryngeal tissues to pepsin can cause further complications, such as esophagitis, ulcers, and even cancer. A fast and accurate diagnosis of reflux can result in patients getting the right treatment at the right time, averting further long-term health problems. By using Peptest as a tool to help accurately diagnose reflux, healthcare professionals can ensure that patients receive the appropriate care and improve the outcomes of their clinical investigations.
What are the benefits of Peptest?
Peptest offers an objective measurement of pepsin as a reliable marker for reflux, which is indicated in a number of diseases. Its simple sample collection process is followed by a rapid and straightforward test that delivers accurate results. As a non-invasive and alternative first line test, Peptest is highly beneficial in the diagnosis and treatment of conditions such as Gastroesophageal reflux disease and Extraoesophageal reflux for medical professionals in several specialties including Gastroenterology, Ear, Nose, and Throat and Respiratory medicine. With quick turnaround times, Peptest facilitates fast and efficient treatment plans for patients. By identifying reflux diseases promptly, medical professionals can develop and implement appropriate treatment plans, enhancing patients’ quality of life.
