Accurate Measurement of Zonulin in Stool Samples
The IDK Zonulin (Stool) ELISA is a quantitative assay designed for the precise determination of zonulin levels in stool samples. Zonulin, a protein intricately involved in intestinal barrier function, has garnered attention as a potential marker for the phenomenon commonly known as “leaky gut” syndrome. This straightforward competitive ELISA employs a biotinylated zonulin tracer and polyclonal anti-zonulin antibodies, ensuring accuracy and reliability in the quantitative analysis of zonulin within stool specimens.
The Role of a Zonulin Stool Test
Zonulin plays a crucial role in regulating the permeability of the intestinal barrier, influencing the integrity of the gut lining. The zonulin stool test quantifies levels in stool samples to provide a unique window into the dynamic interplay between this protein and gut health, offering insights into conditions associated with altered intestinal permeability such as coeliac disease and type-1-diabetes.
Zonulin has emerged as a key player in the context of “leaky gut” syndrome, where increased intestinal permeability may have implications for various health conditions. An increased intestinal permeability, has been associated with metabolic syndrome, obesity, and several autoimmune, inflammatory, and neoplastic diseases. Evidence has also shown that permeability of the intestinal epithelium can have a significant role in diseases including multiple sclerosis, rheumatoid arthritis, asthma, and inflammatory bowel diseases (IBD). The IDK Zonulin (Stool) ELISA facilitates in-depth research, allowing investigators to explore the intricate connections between zonulin stool test levels and the manifestations of compromised gut barrier function.
