Infliximab Free Anti-drug Antibody ELISA (IDKmonitor®)

Product code: K9650 (96 wells)

Determination of free anti-infliximab antibodies

Infliximab is a recombinant protein used to treat inflammatory bowel disease (IBD). This protein can induce humoral immune responses and lead to anti-drug antibody formation which is a major cause of loss of drug response. The IDKmonitor Infliximab Free Anti-drug ELISA kit is a microplate-based quantitative sandwich ELISA for the determination of free anti-infliximab antibodies in plasma or serum samples. Detecting high levels of free anti-infliximab antibodies in patients when the drug level is low (undetectable or sub-therapeutic) may indicate poorer long-term outcomes and suggest the need to switch treatment.

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Key Advantages

Supports the investigation of primary non-response and loss of response to infliximab
Highly sensitive assay that only detects free anti-infliximab antibodies
May help to predict long term outcome of disease
Applicable to both gastroenterology and rheumatology
Automatable on ELISA automates (e.g. Dynex DS2)

Specifications

ELISA

45 tests

Storage: 2-8 °C

Blood sample

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