Laminin – gamma 1-chain

This MAb interacts with the M_r-200,000 γ₁-chain of human-reduced and alkylated laminin; a protein synthesised by cultured cells. The specificity of this antibody was confirmed by immunoprecipitation and ELISA, using a recombinant γ₁-chain. It only reacts with human cells and tissues and, although it does not work in western blotting, it can be used in immunohistochemical staining and immunoprecipitation. Pepsin-digested laminins from human placenta are used as immunogens for antibody production.