This MAb is highly specific to CGRPs, remaining inactive with other neuropeptides. It functions within human and guinea pig tissue, but not rat. It can be used in ELISA, fluorescence microscopy, immunoblotting with BSA-conjugated samples, and other immunohistochemical methods, as well as on frozen sections providing they have undergone perfusion fixation. Paraformaldehyde must be included in the fixative with paraffin sections, if used. A terminal fragment of the CGRP, coupled to BSA with glutaraldehyde, is used as an immunogen for antibody production.