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Ustekinumab Free Anti-drug Antibody ELISA (IDKmonitor®)

Ustekinumab is a fully humanised IgG1 therapeutic monoclonal antibody used for the treatment of Crohn’s disease, ulcerative colitis, plaque psoriasis and psoriatic arthritis. This assay enables the reliable determination of free, unbound anti-drug antibodies.

Key Advantages

Supports the investigation of primary non-response and loss of response to ustekinumab

Highly sensitive assay that detects free anti-ustekinumab antibodies (those unbound to ustekinumab)

May help to predict long term outcome of disease

Applicable to both gastroenterology and rheumatology

Automatable on ELISA automates (e.g. Dynex D2)

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  • Product code: Product code: K9666

Ustekinumab is a fully humanised IgG1 therapeutic monoclonal antibody used for the treatment of Crohn’s disease, ulcerative colitis, plaque psoriasis and psoriatic arthritis. It targets cytokines IL-12 and IL-23 which are involved in immune-mediated inflammatory disorders.

The IDKmonitor Ustekinumab Free Anti-drug Antibody ELISA measures free antibodies against ustekinumab (e.g. STELARA®). This assay enables the reliable determination of free, unbound anti-drug antibodies; therefore it is ideal for therapy monitoring when a measurable ustekinumab concentration is not expected, or the unbound fraction of anti-drug antibodies is required, for example shortly before the next infusion. In combination with the drug level determination, the IDKmonitor® Ustekinumab Free Anti-drug Antibody ELISA supports the monitoring and optimisation of therapy.

  • ELISA

  • 45 tests

  • Storage: 2-8 °C

  • Blood sample