- Product code: Product code: 602070 (20 tests)
The BIOHIT Celiac Quick Test is an advanced lateral flow test (LFT) designed to qualitatively detect anti-tissue transglutaminase (tTG) antibodies (IgA, IgG, IgM) to support the investigation and diagnosis of celiac disease. This highly specific point of care test is for capillary (finger prick) whole blood samples and can be used by healthcare providers in any clinical setting.
A small finger-prick blood sample is applied to the lateral flow test cassette along with a buffer solution immediately after sample collection, and the results become readily visible within ten minutes indicating the presence or absence of anti-tTG antibodies.
The Celiac quick test detects all classes of anti-TTG antibodies due to its novel mode of action, thereby helping eliminate the possibility of false negative results from patients with e.g. IgA deficiency. This test is well-suited for near-patient testing, catering to the needs of general practitioners, gastroenterologists, dieticians, and pharmacists. It proves beneficial in investigating symptoms resembling irritable bowel syndrome (IBS) and aids in the identification of celiac disease in both children and adults.
How to test for Celiac Disease
The conclusive diagnosis of celiac disease relies on distinctive histological alterations observed in intestinal biopsies. Nevertheless, serological tests like the Celiac quick test provide cost-effective and less intrusive diagnostic methods that may negate the necessity for biopsies. In individuals with celiac disease, autoantibodies are generated against endomysium, a constituent of smooth muscle tissue. The primary antigen for anti-endomysium antibodies is tissue transglutaminase (tTG). Human tTG is utilised in serology tests to identify anti-tTG antibodies from a serum sample, forming the foundation for a highly precise celiac screening examination. Such tests prove especially advantageous for paediatric patients, where the threshold for performing upper gastrointestinal endoscopy is higher.