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Ustekinumab Total Anti-drug Antibody ELISA (IDKmonitor®)

Ustekinumab is a fully humanised IgG1 therapeutic monoclonal antibody used for the treatment of Crohn’s disease, ulcerative colitis, plaque psoriasis and psoriatic arthritis. This drug-tolerant assay enables the reliable determination of anti-drug antibodies even in the presence of ustekinumab.

Key Advantages

Supports the investigation of primary non-response and loss of response to ustekinumab

Highly sensitive, drug-tolerant assay that detects total anti-ustekinumab antibodies (those free and bound to ustekinumab)

May help to predict long-term outcome of disease

Identifies patients with low-titre anti-ustekinumab antibodies

Applicable to both gastroenterology and rheumatology

Automatable on ELISA automates (e.g. Dynex D2)

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  • Product code: Product code: K9667

Ustekinumab is a fully humanised IgG1 therapeutic monoclonal antibody used for the treatment of Crohn’s disease, ulcerative colitis, plaque psoriasis and psoriatic arthritis. It targets cytokines IL-12 and IL-23, which are involved in immune-mediated inflammatory disorders.

The IDKmonitor Ustekinumab TOTAL Anti-drug Antibody ELISA measures free and bound antibodies against ustekinumab (e.g. STELARA®). This drug-tolerant assay enables the reliable determination of anti-drug antibodies even in the presence of ustekinumab. This means it is ideal for therapy monitoring when a measurable ustekinumab concentration is expected, for example, shortly after the last infusion. In combination with the drug level determination, the IDKmonitor Ustekinumab TOTAL Anti-drug Antibody ELISA supports the monitoring and optimisation of therapy.

  • ELISA

  • 45 tests

  • Storage: 2-8 °C

  • Blood sample